High purity water generation/distribution system, complete laboratory/pharmaceutical-grade deionized (DI) / high-purity water generation and distribution system

This is a pharmaceutical-grade ultrapure water purification and distribution system designed for producing Water for Injection (WFI) or USP Purified Water compliant with standards like ASTM Type I, ISO 3696, and USP <643>/<645>. It integrates pretreatment, reverse osmosis (RO), continuous electrodeionization (CEDI/EDI), UV disinfection, final filtration, storage, and recirculation in a hot loop configuration to minimize microbial growth.

Key Specifications

• Manufacturer/Integrator: UltraPure Group Ltd. (North Port, FL, USA; est. 2005–2006 build date).

• Model: Alpha Mini 160.

• Serial Number: 1004078.

• Capacity: 250 liters per hour (L/h) ≈ 1,500 L/day or 66 gallons per hour (GPH) of ultrapure water.

• Operating Parameters (from on-site signage):

• RO Unit: A-Permeate 5.0–12.0 µS/cm; B-Product 0.5–5.0 µS/cm; Hardness 0 ppm.

• 2-Micron Filter: 10–12 psi.

• Loop Conductivity: 1.0–18.0 µS/cm.

• TOC: <500 ppb (typically 10–50 ppb in operation).

• Resistivity: >10–18 MΩ·cm (often 18.2 MΩ·cm at 25°C).

• Core Technologies:

• Pretreatment: Multimedia/carbon/softener tanks (blue fiberglass vessels).

• RO: Multi-stage membranes (implied by specs; likely 2-pass for high purity).

• EDI Polishing: XL EDI stack by Electropure (continuous ion removal without chemicals).

• UV Disinfection: Aquafine 254 nm systems with irradiance monitors (multiple units for loop sanitization).

• Final Filtration: 0.2 µm endotoxin-retentive filters.

• Storage/Distribution: 2 × stainless steel (SS316L electropolished) tanks with recirculation pumps.

• Controls/Monitoring:

• Mettler-Toledo Thornton 2000CR conductivity/resistivity analyzers.

• Anatel A-1000 TOC analyzer.

• Allen-Bradley PanelView 600 HMI/PLC.

• ASCO solenoid valves and variable frequency drives (VFDs).

• Build/Compliance: SS304/316 construction; cGMP-compliant; max pressure 150 psi, temp 95°F. Includes safety interlocks, hot water sanitization capability, and warnings for operator training.